| Week | Date | Team | Time | TV |
| Week 1 | Oct. 24, 2020 | @ Indiana Hoosiers | 3:30pm EST | FS1 |
| Week 2 | Oct. 31, 2020 | vs. Ohio State Buckeyes | 7:30pm EST | ABC |
| Week 3 | Nov. 7, 2020 | vs. Maryland Terrapins | 3:30pm EST | BTN |
| Week 4 | Nov. 14, 2020 | @ Nebraska Cornhuskers | 12:00pm EST | FS1 |
| Week 5 | Nov. 21, 2020 | vs. Iowa Hawkeyes | 3:30pm EST | BTN |
| Week 6 | Nov. 28, 2020 | @ Michigan Wolverines | 12:00pm EST | ABC |
| Week 7 | Dec. 5, 2020 | @ Rutgers Scarlet Knights | 12:00pm EST | FS1 |
| Week 8 | Dec. 12, 2020 | vs. Michigan State Spartans | 12:00pm EST | ABC |
| Week 9 | Dec. 19, 2020 | vs. Illinois Fighting Illini | 5:30pm EST | FS1 |
